immediate early genes การใช้

• Thus Homer1a is classified as an immediate early gene.
• The host RNA polymerase initially transcribes two genes, which are called the immediate early genes ( N and cro ).
• They are immediate early genes activated in a ligand-independent manner that bind at the same sites on response elements.
• The more time the mole rats were exposed to a magnetic field the greater the immediate early gene expression within the InGi.
• In other research, variation in the expression of immediate early gene and heat shock protein was identified as causing selective vulnerability.
• The c-fos mRNA and protein is generally among the first to be expressed and hence referred to as an immediate early gene.
• Arc is a member of a class of proteins called immediate early genes ( IEG ) that are rapidly transcribed in response to synaptic input.
• The transition to the next stage of expression is controlled by preventing termination at the ends of the immediate early genes, with the result that the delayed early genes are expressed.
• The lambda gene N, codes for an antitermination protein ( pN ) that is necessary to allow RNA polymerase to read through the terminators located at the ends of the immediate early genes.
• "' Immediate early genes "'( "'IEGs "') are genes which are activated transiently and rapidly in response to a wide variety of cellular stimuli.
• Immediate early genes, which encode proteins that regulate the expression of " early " and " late " viral genes, are the first to be expressed following infection . envelope glycoproteins.
• Granules containing two proteins of known importance to synaptic plasticity, CaMKII ( Calmodulin-dependent Kinase II ) and the immediate early gene Arc, have been identified to associate with a type of the motor protein kinesin, KIF5.
• Some have proposed that an immediate early gene, Zif268, which normally binds to the promoter region of GAD 67 and increases transcription of GAD 67, is lower in schizophrenic patients, thus contributing to decreased levels of GAD 67.
• Klf5 is itself regulated by the immediate early gene egr-1 in VSMCs, which, if similarly regulated in the cardiomyocyte, places Klf5 potentially in a position to co-ordinate the acute response to external stress and tissue remodelling in the myocardium.
• The researchers did not set out to study nurturing; rather, they were curious about fosB, because it is one of many " immediate early genes, " which are thought to be crucial players in learning, memory and other types of behavioral change.
• It is also, Greenberg said, some of the first evidence that members of a small, poorly understood family of genes, called immediate early genes, are crucial in orchestrating a mammal's complex response to environmental stimuli _ in this case, the sight and smell of its newborn progeny.